Written in English
|Statement||by Jan Ross Turner.|
|The Physical Object|
|Pagination||41 leaves, bound :|
|Number of Pages||41|
Biosynthesis of Sterols by a Yeast Homogenate Incorporation of Mevalonic Acid into Cholesta‐5,7,24‐trien‐3β‐ol and 5α‐Cholesta‐7,24‐dien‐3β‐ol. Jacques P. MOREAU. Worcester Foundation for Experimental Biology Inc., Maple Avenue, Shrewsbury, Massachusetts, U.S.A. Cited by: 7. Steryl Ester Sterol Biosynthesis Ergosterol Biosynthesis Squalene Epoxidase Membrane Fatty Acid Composition These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm by: 3. Although the specific function of the sterols in yeast is not clear (Boll et al., ), some evidence has been presented suggesting that sterol synthesis and development of respiratory capacity. The study of sterols is of both practical and theoretical interest, being important in the analysis of the action of antifungal compounds, in vitamin D production and investigating the role of sterols in cell division, mating (), and ethanol extraction of sterols from yeast is both rapid and simple, the effectiveness of the basic method being reflected by the fact that it has not.
Gaber RF, Copple DM, Kennedy BK, Vidal M, Bard M. The yeast ERG6 is required for normal membrane function but is not essential for biosynthesis of the cell-cycle sparking sterol. Mol Cell Biol ;– PubMed Google Scholar. Yeast is one of the most studied laboratory organisms and represents one of the most central models to understand how any eukaryote cell works. On the other hand, yeast fermentations have for millennia provided us with a variety of biotech products, like wine, beer, vitamins, and recently also with pharmaceutically active heterologous products and biofuels. INTRODUCTION. Most eukaryotic cells contain and synthesize sterols. Whereas cholesterol is the unique sterol of vertebrates and ergosterol the major sterol of most fungi and some unicellular algae, most higher plants contain a complex mixture in which cholesterol is a minor component and ethyl sterols (sitosterol and stigmasterol) account for more than 60% and methyl sterols account for. Included in the same study  was 2,3-iminosqualene (14, is, MM pea enzyme, yeast enzyme), a compound used to block sterol biosynthesis in S. cerevisiae  and Gibberella fujikuroi  in a study of the sterol requirements of these organisms.
The yeast Saccharomyces cerevisiae was a powerful tool in the identification of the structural genes involved in sterol biosynthesis in eucaryotes. Among 20 genes, 16 were isolated by genetic techniques using either complementation of mutants or overexpression strategy using specific inhibitors. In Cited by: 3. PHYSIOLOGICAL IMPLICATIONS OF STEROL BIOSYNTHESIS IN YEAST. Annual Review of Microbiology Vol. (Volume publication date October ) Annual Review of Genetics Sterol Biosynthesis P Benveniste Annual Review of Plant Physiology BIOSYNTHESIS AND ACCUMULATION OF STEROLS. Sterol control of phospholipid biosynthesis in yeast. Sterol control of phospholipid biosynthesis in yeast Prog Clin Biol Res. ; Author K Bloch 1 Affiliation 1 Department of Chemistry, Harvard University, Cambridge, Massachusetts PMID: No abstract available. PREFACE THE suggestion that there should be a Ciba Foundation symposium on the biosynthesis of sterols had been put forward whenever opportunity offered over several years by Professor K. Bloch, Dr. G. PopjSk and Professor S. Bergstrom. A further stimulus occurred when Dr. K. Folkers and his group published their work on the synthesis of mevalonic acid.